Why the immediate postpartum period matters After the placenta is delivered, the uterus must contract to compress the blood vessels at the placental site. This process, together with shifts in blood volume and vascular tone, explains why the mother can appear well yet still develop significant bleeding or cardiovascular instability. The first 24 hours therefore […]
The immediate hormonal transition Pregnancy is characterized by very high concentrations of placental estrogen and progesterone. After the placenta is delivered, both hormones decline rapidly over the following days. This withdrawal is one of the most abrupt endocrine transitions in human physiology. Estrogen and progesterone interact with neurotransmitter systems involved in mood, anxiety, sleep, and […]
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