A–Z Glossary

Narrow therapeutic index

A narrow therapeutic index means the amount of medicine that helps and the amount that may be toxic are close together.

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Effects on baby safety and monitoring of medications

Effects on baby safety and monitoring of medications

Why medication safety is different for newborns Medication safety in babies begins with a central principle: neonatal physiology changes the risk profile of almost every drug. A newborn has higher total body water, lower fat stores, variable protein binding, immature hepatic enzyme activity, and developing renal clearance. Premature babies have even less reserve, and critically […]